|
KMID : 0358219940210020137
|
|
Korean Journal of Fertility and Sterility
1994 Volume.21 No. 2 p.137 ~ p.148
|
|
|
Cryopreservation of Human Embryos for Assisted Reproductive Technology
|
|
문신용
김정훈/김석현/최영민/신창재/김정구/장윤석
|
|
|
Abstract
|
|
|
Controlled ovarian hyperstimulation (COH) for in vitro fertilization and embryo transfer (IVF-ET) often results in the production of more embryos than can be efficaciously transferred at one time. However, embryo cryopreservation provides a
mechanism by
which additional embryos can be stored for later thawing and transfer.
From November, 1990 to October, 1992, we completed 42 transfer cycles of cryopreserved pronucleus (PN) 1-cell embryos using the fixed protocol of hormonal replacement therapy in a physiological manner regardless of individual ovarian function.
Artificial endometrial stimulation was performed with only exogenous estradiol and progesterone (E-P) in 36 transfer cycles (Group Ⅰ) and with gonadotropin-releasing hormone agonist (GnRHa) and exogenous estradiol and progesterone (GEEP) in 6
transfer
cycles (Group Ⅱ). @ES The results were as follows.
@EN 1. The Survival rate of total cryopreserved-thawed embryos was 64.9% (198/305): 64.9% (172/265) in Group Ⅰ and 65.0% (26/40) in Group Ⅰ and 65.0% (26/40) in GroupⅡ.
2. Total 168 embryos were transferred with an average of 4.7 per ET in Group Ⅰ and total 26 embryos were transferred with an average of4.3 per ET in Group Ⅱ.
3. The pregnancy rate (PR) per cryopreserved-thawed ET and the implantation rate was 33.3% (14/42) and 6/7% (13/194), respectively. The PRs per cryopreserved-thawed ET were 30.6% (11/36) in Group Ⅰ and 50.0% (3/6) in Group Ⅱ without significant
difference.
4. The take home baby rate was 11.1% (4/36) in Group Ⅰand 33.3% (2/6) in Group Ⅱ.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|